Search results for "Calcium phosphate cement"

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Novel Biodegradable Composite of Calcium Phosphate Cement and the Collagen I Mimetic P-15 for Pedicle Screw Augmentation in Osteoporotic Bone

2021

Osteoporotic vertebral fractures often necessitate fusion surgery, with high rates of implant failure. We present a novel bioactive composite of calcium phosphate cement (CPC) and the collagen I mimetic P-15 for pedicle screw augmentation in osteoporotic bone. Methods involved expression analysis of osteogenesis-related genes during osteoblastic differentiation by RT-PCR and immunostaining of osteopontin and Ca2+ deposits. Untreated and decalcified sheep vertebrae were utilized for linear pullout testing of pedicle screws. Bone mineral density (BMD) was measured using dual-energy X-ray absorptiometry (DEXA). Expression of ALPI II (p &lt

Collagen imusculoskeletal diseasesmedicine.medical_specialtyQH301-705.5OsteoporosisMedicine (miscellaneous)General Biochemistry Genetics and Molecular BiologyArticleInternal medicinemedicineOsteopontinBiology (General)Calcium phosphate cementBone mineralosteoporotic vertebral fracturesbiologyChemistrytechnology industry and agricultureImplant failurecalcium phosphate cementmedicine.diseasemusculoskeletal systemosteoporosispolymethylmethacrylateEndocrinologybiology.proteinOsteoporotic boneOsteocalcincollagen I mimetic P-15Biomedicines

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